Sepsis Unmasked: From Cells to Sirens (6.23.2025)-Slide deck 2

Slide deck 2

Pdf Summary

The document provides a detailed understanding of sepsis and associated medical conditions, presented by Mano Patri MD and Maya Patri EMT. Sepsis is a life-threatening clinical syndrome caused by physiologic, biologic, and biochemical abnormalities due to infection. It can be caused by bacteria, viruses, and fungi, with the former responsive to antibiotics. However, incorrect antibiotic use can lead to drug resistance and adverse effects.<br /><br />Several medical conditions leading to sepsis are highlighted, including meningitis, cellulitis, Clostridioides difficile infections, urinary tract infections (UTIs), puncture wounds, and infectious rashes. Each condition is expanded upon with symptoms, potential complications, and treatment considerations. For instance, Clostridioides difficile is primarily triggered by antibiotic use and can lead to severe diarrhea and colitis, with high mortality rates if not addressed.<br /><br />Clinical presentations are provided, such as the case of a 30-year-old with meningococcal meningitis, a 40-year-old with leg lymphedema and venous stasis dermatitis, and an 80-year-old with possible UTI. These cases illustrate the complexity and variety of sepsis presentations and the importance of thorough patient history and physical examination for diagnosis.<br /><br />Diagnosis issues, particularly incorrect antibiotic use leading to misdiagnosis, are discussed. The SBAR (Situation, Background, Assessment, Recommendation) framework is suggested for structured clinical assessment and management, promoting accurate diagnosis and treatment.<br /><br />Infectious conditions like disseminated shingles, measles, and MPox are mentioned for their airborne transmission risks. The document emphasizes proper use of protective measures, such as N95 masks, to prevent disease spread. Ultimately, it underlines the importance of considering infectious possibilities, appropriate antibiotic use, differential diagnosis, and staying updated with current medical literature to enhance patient care and reduce sepsis-related morbidity and mortality.

Keywords

sepsis

antibiotic resistance

clinical syndrome

infection

diagnosis

SBAR framework

Clostridioides difficile

meningococcal meningitis

protective measures

patient care